Potential Chemotherapeutics. I. Hydrazine Derivatives, Structurally Related to 1-Benzoxythiocarbo-2-salicylidene Hydrazine.
نویسندگان
چکیده
منابع مشابه
1-(2-Furylmethylene)-2-(2-nitrophenyl)hydrazine
The title Schiff base compound, C(11)H(9)N(3)O(3), was obtained from a condensation reaction of furan-2-carbaldehyde and 2-nitro-phenyl-hydrazine. The mol-ecule is roughly planar, the largest deviation from the mean plane defined by all non-H atoms being 0.097 (4). An in ntra-molecular N-H⋯O hydrogen bond might influence the planar conformation of the mol-ecule. In the crystal, weak C-H⋯O hydro...
متن کاملEnzymatic Activation of Hydrazine Derivatives
The oxidative metabolism of hydralazine, isoniazid, iproniazid, and phenylhydrazine has been studied using spin-trapping techniques. The oxidation of these hydrazine derivatives, catalyzed by horseradish peroxidase and prostaglandin synthetase, produces reactive free radical intermediates. Enzymatic activation of hydralazine produce the nitrogen-centered hydralazyl radical (RNHNH.); phenylhydra...
متن کامل1-(2-Chlorobenzylidene)-2-(2,4-dinitrophenyl)hydrazine
In the title compound, C(13)H(9)ClN(4)O(4), there are two crystallographically independent mol-ecules in the asymmetric unit, which have very similar conformations. The C=N-N angles in each independent mol-ecule are 115.0 (2) and 116.6 (2)°, which are significantly smaller than the ideal value of 120° expected for sp(2)-hybridized N atoms. This is probably a consequence of repulsion between the...
متن کامل[1-Phenyl-2-(4-pyridyl)ethylidene]hydrazine
The title compound, C(13)H(13)N(3), is non-planar, with the pyridine and phenyl rings inclined at an angle of 80.7 (3)°. The central ethyl-idenehydrazine atoms lie in a plane [mean deviation = 0.013 (1) Å], which forms dihedral angles of 88.5 (1) and 9.4 (1)° with the pyridine and phenyl rings, respectively. In the crystal structure, mol-ecules are linked by inter-molecular N-H⋯N hydrogen bonds...
متن کامل1-(2,3-Dimethoxybenzylidene)-2-(2,4-dinitrophenyl)hydrazine
In the title compound, C(15)H(14)N(4)O(6), the dihedral angle between the aromatic rings is 3.7 (4)°. The nitro groups make dihedral angles of 6.0 (4) and 5.2 (4)° with the parent ring and are oriented at 6.0 (6)° with respect to each other. The meth-oxy groups are inclined at 54.0 (2) and 2.5 (3)° with respect to the benzene ring to which they are attached. In the crystal, mol-ecules are linke...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1960
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.14-1025